Target flexibility: an emerging consideration in drug discovery and design.

TitleTarget flexibility: an emerging consideration in drug discovery and design.
Publication TypeJournal Article
Year of Publication2008
AuthorsCozzini, Pietro, Kellogg Glen E., Spyrakis Francesca, Abraham Donald J., Costantino Gabriele, Emerson Andrew, Fanelli Francesca, Gohlke Holger, Kuhn Leslie A., Morris Garrett M., Orozco Modesto, Pertinhez Thelma A., Rizzi Menico, and Sotriffer Christoph A.
JournalJ Med Chem
Volume51
Pagination6237-55
Date Published2008 Oct 23
ISSN1520-4804
KeywordsAnimals, Biomolecular, Computer Simulation, Crystallography, Drug Design, Drug Evaluation, Humans, Nuclear Magnetic Resonance, Pharmaceutical Preparations, Preclinical, Proteins, X-Ray
DOI10.1021/jm800562d