8-Amino guanine accelerates tetramolecular G-quadruplex formation.
| Title | 8-Amino guanine accelerates tetramolecular G-quadruplex formation. |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Gros, Julien, Aviñó Anna, de la Osa Jaime Lopez, González Carlos, Lacroix Laurent, Pérez Alberto, Orozco Modesto, Eritja Ramon, and Mergny Jean-Louis |
| Journal | Chem Commun (Camb) |
| Pagination | 2926-8 |
| Date Published | 2008 Jul 7 |
| ISSN | 1359-7345 |
| Keywords | Base Sequence, Circular Dichroism, G-Quadruplexes, Guanine, Molecular Structure, Nucleic Acid Denaturation, Temperature |
| Abstract | We demonstrate here that 8-amino guanine () strongly accelerates quadruplex formation, which makes this nucleobase the most attractive replacement for guanine in the context of tetramolecular parallel quadruplexes. |
| DOI | 10.1039/b801221k |