Last most-relevant publications
- DNA double-strand break-derived RNA drives TIRR/53BP1 complex dissociation Cell Reports
- MiOS, an integrated imaging and computational strategy to model gene folding with nucleosome resolution Nat Struct Mol Biol
- DNAffinity: a machine-learning approach to predict DNA binding affinities of transcription factors Nucleic Acids Res
- BioExcel Building Blocks Workflows (BioBB-Wfs), an integrated web-based platform for biomolecular simulations Nucleic Acids Res
Prediction and validation of protein intermediate states from structurally rich ensembles and coarse-grained simulations
Multiscale simulation of DNA
DNA is not only among the most important molecules in life, but a meeting point for biology, physics and chemistry, being studied by numerous techniques. Theoretical methods can help in gaining a detailed understanding of DNA structure and function, but their practical use is hampered by the multiscale nature of this molecule.