Recent advances in the study of nucleic acid flexibility by molecular dynamics.

TitleRecent advances in the study of nucleic acid flexibility by molecular dynamics.
Publication TypeJournal Article
Year of Publication2008
AuthorsOrozco, Modesto, Noy Agnes, and Pérez Alberto
JournalCurr Opin Struct Biol
Volume18
Pagination185-93
Date Published2008 Apr
ISSN0959-440X
KeywordsBase Pairing, Computer Simulation, Models, Molecular, Nucleic Acids, Time Factors
Abstract

The recent use of molecular dynamics (MD) simulations to study flexibility of nucleic acids has been reviewed from an analysis of the publications appearing in the past two years (from 2005 till date). Despite the existence of some unsolved problems in the methodologies, these years have been witness to major advances in the field. Based on a critical review of the most recent contributions, excitement exists on the expected evolution of the field in the next years.

DOI10.1016/j.sbi.2008.01.005
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