Last most-relevant publications
- Splice variants of mitofusin 2 shape the endoplasmic reticulum and tether it to mitochondria Science
- Controlled sulfur-based engineering confers mouldability to phosphorothioate antisense oligonucleotides Nucleic Acids Research
- Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway Nature Communications
- Correlated motions in DNA: beyond base-pair step models of DNA flexibility Nucleic Acids Research
A study by the scientists Xavier Salvatella and Modesto Orozco at IRB Barcelona reveals the existence of information highways that connect and correlate distant sites within a single protein.
Published in Nature Communications, the article furthers a key theoretical field for drug discovery, as it would allow the discovery of many more drug binding sites in proteins of biomedical interest.