Last most-relevant publications
- Probing allosteric regulations with coevolution-driven molecular simulations Science advances
- Impact of DNA methylation on 3D genome structure Nature Communications
- 4D Genome Rewiring during Oncogene-Induced and Replicative Senescence Molecular Cell
- Emergence of chromatin hierarchical loops from protein disorder and nucleosome asymmetry Proceedings of the National Academy of Sciences
A study by the scientists Xavier Salvatella and Modesto Orozco at IRB Barcelona reveals the existence of information highways that connect and correlate distant sites within a single protein.
Published in Nature Communications, the article furthers a key theoretical field for drug discovery, as it would allow the discovery of many more drug binding sites in proteins of biomedical interest.