Last most-relevant publications
- Mechanism of reaction of RNA-dependent RNA polymerase from SARS-CoV-2 Chem Catalysis
- Probing allosteric regulations with coevolution-driven molecular simulations Science advances
- Impact of DNA methylation on 3D genome structure Nature Communications
- 4D Genome Rewiring during Oncogene-Induced and Replicative Senescence Molecular Cell
Researchers measure a property of DNA for the first time
ParmBSC1 force-field
ParmBSC1 forcefield, a refined force-field for the atomistic simulation of DNA.
When a denaturant stabilizes DNA
The transmission of information via proteins could revolutionize drug discovery
A study by the scientists Xavier Salvatella and Modesto Orozco at IRB Barcelona reveals the existence of information highways that connect and correlate distant sites within a single protein.
Published in Nature Communications, the article furthers a key theoretical field for drug discovery, as it would allow the discovery of many more drug binding sites in proteins of biomedical interest.