Last most-relevant publications
- DNA double-strand break-derived RNA drives TIRR/53BP1 complex dissociation Cell Reports
- MiOS, an integrated imaging and computational strategy to model gene folding with nucleosome resolution Nat Struct Mol Biol
- DNAffinity: a machine-learning approach to predict DNA binding affinities of transcription factors Nucleic Acids Res
- BioExcel Building Blocks Workflows (BioBB-Wfs), an integrated web-based platform for biomolecular simulations Nucleic Acids Res
A study by the scientists Xavier Salvatella and Modesto Orozco at IRB Barcelona reveals the existence of information highways that connect and correlate distant sites within a single protein.
Published in Nature Communications, the article furthers a key theoretical field for drug discovery, as it would allow the discovery of many more drug binding sites in proteins of biomedical interest.