Last most-relevant publications
- Molecular stripping underpins derepression of a toxin–antitoxin system Nat Struct Mol Biol
- Structural basis of a redox-dependent conformational switch that regulates the stress kinase p38α Nature Communications
- Nucleic acids in modern molecular therapies: A realm of opportunities for strategic drug design Current Opinion in Structural Biology
- Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair Nature Communications
Prediction and validation of protein intermediate states from structurally rich ensembles and coarse-grained simulations
Multiscale simulation of DNA
DNA is not only among the most important molecules in life, but a meeting point for biology, physics and chemistry, being studied by numerous techniques. Theoretical methods can help in gaining a detailed understanding of DNA structure and function, but their practical use is hampered by the multiscale nature of this molecule.